Los Angeles Chargers linebackeris expected to miss four to six weeks with an ankle injury, a source told ESPN's Adam Schefter.
Perryman hobbled off the field Sunday after injuring his left ankle in the first quarter in the Chargers' preseason game against Seattle. He was taken to the locker room on a cart and returned to the sideline using crutches and wearing a walking boot.
As ESPN noted, A long-term injury to Perryman would be another significant blow to the Chargers, who have been hit with multiple injuries this preseason. Not only that, but the Chargers may unofficially be the most unlucky team in football over the past five seasons when it comes to devastating injuries to key players.
Schefter said Perryman will undergo an MRI on Monday.
Perryman, 24, was slated to be Los Angeles' starting middle linebacker after recording 72 tackles, two sacks and an interception in 12 games last year.
The Chargers already are without rookie receiver, who will miss training camp while recovering from a lower back disk herniation. Coach Anthony Lynn said last week that Williams, the Chargers' first-round draft pick, has resumed running and is making progress.
Los Angeles also will be without the services of rookie guard, the team's second-round pick, who has a torn ACL in his right knee.